Peer-reviewed publications

E Ahrman, P Lorenzo, K Holmgren, A Grodzinsky, LE Dahlberg, T Saxne, D Heinegård, P Onnerfjord: Novel Cartilage Oligomeric Matrix Protein (COMP) Neoepitopes Identified in Synovial Fluids from Patients with Joint Diseases Using Affinity Chromatography and Mass Spectrometry. Journal of Biological Chemistry 289(30), 2014, 20908-20916. 

H Boeth, GN Duda, MO Heller, RM Ehrig, R Doyscher, T Jung, P Moewis, S Scheffler, WR Taylor: Anterior Cruciate Ligament-Deficient Patients With Passive Knee Joint Laxity Have a Decreased Range of Anterior-Posterior Motion During Active Movements. American Journal of Sports Medicine 41(5), 2013, 1051-57.

LA Crowe, F Tobalem, A Gramoun, BMA Delattre, K Grosdemange, J Salaklang, A Redjem, A Petri-Fink, H Hofmann, J-P Vallée: Improved dynamic response assessment for intra-articular injected iron oxide nanoparticles. Magnetic Resonance in Medicine 68(5), 2012, 1544–52.

SG Dakin, RK Smith, D Heinegård, P Önnerfjord, A Khabut, J Dudhia: Proteomic analysis of tendon extracellular matrix reveals disease stage-specific fragmentation and differential cleavage of COMP. J Biol Chem 289(8), 2014, 4919-4927.

RG Digigow, J-F Dechézelles, J Kaufmann, D Vanhecke, J Knapp, M Lattuada, B Rothen-Ruthishauser, A Fink: Magnetic microreactors for efficient and reliable magnetic nanoparticles surface functionalization. Lab on a Chip 14(13), 2014, 2276-2286.

F Eckstein, H Boeth, G Diederichs, W Wirth, M Hudelmaier, S Cotofana, M Hofmann-Amtenbrink, GN Duda: Longitudinal change in femorotibial cartilage thickness and subchondral bone plate area in male and female adolescent vs. mature athletes. Annals of Anatomy 2013 Dec 24 [Epub ahead of print].

F Eckstein, A Guermazi, G Gold, J Duryea, MP Hellio Le Graverand, W Wirth, CG Miller: Imaging of cartilage and bone: promises and pitfalls in clinical trials of osteoarthritis. Osteoarthritis Cartilage 22(19), 2014, 1516-1532.

F Eckstein, W Wirth, LS Lohmander, M Hudelmaier, RB Frobell: Five-year follow-up of knee joint cartilage thickness changes after acute anterior cruciate ligament rupture. Arthritis Rheumatol. 2014 Sep 23. [Epub ahead of print]

A Gramoun, LA Crowe, L Maurizi, W Wirth, F Tobalem, K Grosdemange, G Coullerez, F Eckstein, M Koenders, W Van den Berg, H Hofmann, J-P Vallée: Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages. Arthritis Research & Therapy 16(3) R131, 2014.  

T Gaber, CL Tran, S Schellmann, M Hahne, C Strehl, M Jakstadt, GR Burmester, F Buttgereit: Patophysiological hypoxia affects both redox state and IL-2 signaling of human CD4+ T cells and concomitantly impairs survival and proliferation. Ann Rheum Dis, 72(Suppl3), 2013, 793.

L Haglund, V Tillgren, P Önnerfjord, D Heinegård: The C-terminal peptide of chondroadherin modulates cellular activity by selectively binding to heparan sulfate chains.  Journal of Biological Chemistry 288(2), 2013, 995-1008.

H Hofmann, M. Hofmann-Amtenbrink: Nanotechnologie in der Medizin: Europäische Forschung und ihre Auswirkungen. In: Tag, B., Mausbach, J. (editors): Nanomedizin – Interdisziplinäre Betrachtungen. VDG Weimar, 2014, 19-50.

M Hofmann-Amtenbrink, H Hofmann, A Hool, F Roubert: Nanotechnology in medicine: European research and its implications. Swiss Medical Weekly 144, 2014.

A Hool, M-G Beuzelin Ollivier, F Roubert: Managing Operating Procedures in Distributed Collaborative Projects. Journal of Physics: Conference Series 429, 2013, 012071.

M Mahmoudi, H Hofmann, B Rothen-Rutishauser, A Petri-Fink: Assessing the in vitro and in vivo toxicity of Superparamagnetic Iron Oxide Nanoparticles. Chemical Review 4(112), 2012, 2323–38.

L Maurizi, U Sakulkhu, LA Crowe, VM Dao, N Leclaire, JP Vallée, Heinrich Hofmann: Syntheses of cross-linked polymeric superparamagnetic beads with tunable properties. RSC Advances 4(22), 2014, 11142-11146.

L Maurizi, U Sakulkhu, A Gramoun, J-P Vallée, H Hofmann: A fast and reproducible method to quantify magnetic nanoparticle biodistribution. Analyst, 2014.

C Müller, A Khabut, J Dudhia, FP Reinholt, A Aspberg, D Heinegård, P Önnerfjord: Quantitative proteomics at different depths in human articular cartilage reveals unique patterns of protein distribution. Matrix Biol. 2014, Sep 1. [Epub ahead of print]

P Önnerfjord, A Khabut, FP Reinholt, O Svensson, D Heinegård: Quantitative proteomic analysis of eight cartilaginous tissues reveals charateristic differences as well as similarities between subgroups. Journal of Biological Chemistry 287(23), 2012, 18913–24.

A Petri-Fink, B. Rothen-Rütishauser: Nanoparticles and Cells: An Interdisciplinary Approach. Chimia 66(3), 2012, 104-109. 

F Roubert, M-G Beuzelin-Ollivier, M Hofmann-Amtenbrink, H Hofmann, A Hool: “Nanostandardization” in Action: Implementing Standardization Processes in a Multidisciplinary Nanoparticle-Based Research and Development Project. NanoEthics ()1-22, , 2016, doi 10.1007/s11569-015-0248-8

U Sakulkhu, L Maurizi, M Mahmoudi, M Motazacker, M Vries, A Gramoun, M.-G. Ollivier Beuzelin, J.-P. Vallée, F. Rezaee, H. Hofmann: Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats. Nanoscale 6(19), 2014, 11439-11450.

U Sakulkhu, M Mahmoudi, L Maurizi, G Coullerez, M Hofmann, F Rezaee, MM Motazacker, M. Vries, H. Hofmann: Significance of surface charge and shell material of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) based core/shell nanoparticles on the composition of the protein corona. Biomaterials Science, 2015.

U Sakulkhu, M Mahmoudi, L Maurizi, J Salaklang, H Hofmann: Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings. Scientific Reports 4 (22), 2014.

S Schellmann, T Gaber, M Jakstadt, C Stahn, M Hahne, M Wagegg, P Maschmeyer, M Fangradt, P Kolar, GR Burmester, F Buttgereit: Hypoxia affects the redox state of CD4+ T cells and concomitantly impairs survival and proliferation. Ann Rheum Dis, 69(Suppl3), 2010, 329.

F Schulze, A Dienelt, S Geissler, P Zaslansky, J Schoon, K Henzler, P. Guttmann, A. Gramoun, L. A Crowe, L. Maurizi, J.‐P. Vallée, H. Hofmann, G. N Duda, A. Ode: Amino‐polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles are Suitable for Monitoring of Human Mesenchymal Stromal Cells In Vivo. Small, 2014.

C Strehl, T Gaber, L Maurizi, M Hahne, R Rauch, P Hoff, T Häupl, M Hofmann-Amtenbrink, A R Poole, H Hofmann, F Buttgereit: Effects of PVA coated nanoparticles on human immune cells. International Journal of Nanomedicine 10, 2015 Journal of Biological Chemistry 289(30), 2014, 3429-3445.

C Strehl, T Gaber, M Wagegg, M Jakstadt, M Hahne, S Schellmann, B Esche-Szostak, G Coullerez, H Hoffmann, GR Burmester, F Buttgereit: Influence of PVA coated nanoparticles on survival and functionality of human immune cells. Ann Rheum Dis, 71(Suppl3), 2012, 640.

AE Tamm, M Lintrop, Y Hansen, J Kumm, AO Tamm: Associations between KOOS (Knee Injury and Osteoarthritis Outcome Score) and bone-cartilage biomarkers. BONE, 28 (2), 2011, S261.

AE Tamm, M Lintrop, Y Hansen, J Kumm, AO Tamm: Correlations between bone and cartilage biomarkers and activity limitations in females with early knee osteoarthritis. Estonian Medical Journal 90 (11), 2011, 54.

AO Tamm, J Kumm, M Lintrop, M Vija, M Vähi, AE Tamm: Factors associated with early knee osteoarthritis. Estonian Medical Journal, 90 (11), 2011, 53.

M Wagegg, T Gaber, F Lohanatha, M Jakstadt, G Kasper, G Duda, P Kolar, GR Burmester, F Buttgereit: Hypoxia promotes adipogenic and promotes osteogenic differentiation of human mesenchymal stromal cells in a HIF-1 dependent manner. Arthritis & Rheumatism 62, 10 (Supplement), 2010, S262-S263.

M Wagegg, T Gaber, F Lohanatha, M Jakstadt, G Kasper, G Duda, P Kolar, GR Burmester, F Buttgereit: Hypoxia suppresses adipogenic and promotes osteogenic differentiation of human mesenchymal stem cells (HMSCS) in a HIF-1 dependent manner. Ann Rheum Dis, 69(Suppl3), 2010, 613.

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News

DG Growth on NanoDiaRA

"An inside view of arthritis",15 February 2016 

Read report on the Website of the European Commission

Final Project Group Meeting in Leuven

19 February, 2014
Further information

NANOFOL – NanoDiaRA Conference in the 7th Framework Programme

20–21 November, 2013
Further information

 

Find more news in the news archive.

Contact

Administrative Coordination

Priv.-Doz. Dr. med. Felix Thiele, M. Sc.
Europäische Akademie zur Erforschung von Folgen wissenschaftlich-technischer Entwicklungen Bad Neuenahr-Ahrweiler GmbH
Wilhelmstr. 56
53474 Bad Neuenahr-Ahrweiler
Germany

felix.thiele|please replace this part with an email-at|ea-aw.de
www.ea-aw.org

Europäische Akademie zur Erforschung von Folgen wissenschaftlich-technischer Entwicklungen Bad Neuenahr-Ahrweiler GmbH

Scientific Coordination

Margarethe Hofmann-Amtenbrink Dr.-Ing.
Mat Search Consulting Hofmann

Ch. Jean Pavillard 14
1009 Pully
Switzerland

mhofmann|please replace this part with an email-at|matsearch.ch
www.matsearch.ch

Mat Search Consulting Hofmann